Abstract: The ore bodies in Zhilingtou Au-Ag deposit,Zhejiang Province, are chalcedonic quartz veins containing adularia and rhodonite The ores occur in circular-zonal structure and grained,metasomatic and poikiloblastic texture Wall rocks are strongly altered and with typical features of epithermal alteration Ore-forming fluid is low-salinity,approximate neutral and reduced hydrothermal The S and Pb isotopes of the Au-Ag doposit suggest that the ore forming materials are mostly from deep crust(down to upper mantle) The ore-forming hydrothermal is derived from magmatic water and meteoric water,and evolves as low temperature hydrothermal suggested by H,O and C isotopes The mineralization of Zhilingtou Au-Ag doposit are genetically associated with hypabyssal magmatic activities in Caledonian period It is a typical epithermal or sub volcanic hydrothermal Au-Ag deposit.