Abstract: East Harbin area in Heilongjiang Province is famous for its Cu-Pb-Zn-Mo mineralization belt. Based on the East Harbin geochemical block, which is delineated by the ultra-low density geochemical survey with metal activity measuring, this study predicts the mineral resources potential of Au, Ag, Pb and W within the block applying the method of quantitative assessment modal for ore-forming usable metal. The resources volume by the prediction is much greater than the total reserves of the deposits that hawe been found, showing the result is reasonable. This prediction is a significant reference and guide for further mineral exploration.