Abstract: De-interfered anomalous principal component thresholding is a unique technique created in the extraction for RS anomalies of mineralized alteration and application study. It makes large-scaled projects of extracting mineral anomalies possible. The technique, which consists of three main parts:pre-processing, information extraction and postprocessing, has been in successful operation for the systems of PCI and ENVI. After repeated testing, the authors have achieved the technology in the Erdas system. This method is applied in 1:50000 mineral resources survey in Chabaqi, Inner Mongolia. The result has proved the feasibility of the method.