Abstract: The Northeast China epicontinental region is tectonically located in the compounding part of Paleo-Asia Oceanic and marginal-Pacific tectonic domains, where the tectonomagmatic activities are intense, with developed nonferrous and precious metal deposits. Based on the study of geology and geochemistry of typical mineral deposits with the theory and method of metallogenic system, the paper discusses the origin, migration and enrichment regularities of ore-forming materials considering the fluid concentration, eruption or boiling. The metallogenic dynamics models of different forming conditions and spatial-temporal evolution are preliminarily identified, i.e. the model for Archean nuclear evolution and massive sulfide ores, the model for Proterozoic rift basin evolution and stratiform Pb-Zn deposits, the model for Paleozoic Paleo-Asian Oceanic forming-closing and massive sulfide ores, and the model for Mesozoic lithosphere evolution and nonferrous and precious metallic deposits.