Abstract: The large scale Dachang antimony orefield is located in the southwest of Guizhou Province. The Upper Permian "Dachang layer" is the major ore-bearing layer. The orebodies occur mainly in the top of the strongly altered secondary quartzite and the lower part of clay rock. The regional NE-trending faults and second-order folds and faults are the major ore-controlling structures. The tenso-shear faults and interstratified faults are developed, serving as important host structures. Based on the ore-controlling factors in the orefield, two prospective targets are delineated.