Abstract: The metallogenesis of Qingchengzi Pb-Zn deposits is controlled by strata and rock formation. The dome structure caused by the emplacement of Paleoproterozoic granite, the ductile shear zone and interlayer fault in overlying stratiform rock series, and the Mesozoic magmatism and fault structure significantly contribute to the metallogenesis. The ore deposits are of complex polystage, with three metallogenic epochs during the periods of Paleoproterozoic synsedimentation emplacement, Luliangian metamorphic-deformation re-emplacement and Mesozoic tectonomagmatic reemplacement, respectively. The deposits are genetically stratabound ones with metamorphism-deformation and hydrothermal superimposition on the basis of submarine (spout) hydrothermal deposition, belonging to submarine exhalation sedimentary metamorphic-magmatic hydrothermal reformation type.