Abstract: The copper and gold deposits in Dayaoshan area of Guangxi Region occur mainly in Cambrian strata. The CuAu mineralization is genetically related to the Caledonian and Yanshanian tectonomagmatic activities. Based on the results of previous geological survey and researches, the metallogenic conditions for the Cu-Au polymetal deposits related to hypabyssal and super-hypabyssal igneous rocks are analyzed from the view of sedimentary formation, magmatic rock, tectonomagmatic activity, ore-forming fluid, trace element and sulfur isotopic characteristics. It is concluded that the deposits in the area genetically belong to sedimentary enrichment-fault structure-hydrothermal overlapping reformation type. The metallogenesis underwent early stage of sedimentary enrichment, middle stage of magmatic hydrothermal overlapping mineralization and end stage of post-magmatic fault and hydrothermal reformation.