Abstract: The Weizigou gold deposit, occurring in the ancient metamorphic rocks of Jiamushi Uplift, Ji-Hei Geosynclinal System, is a migmatized hydrothermal gold deposit. Study on the geological features of the deposit, with analysis of the source of ore-forming material, type and genesis, shows that the deposit is mainly controlled by the NE-and NNE-trending faults in the region. The metallogenic substance is derived mainly from the Paleoproterozoic Jiantang formation and Liumao formation. On this basis, the metallogenic mechanism is discussed. The metallogenesis in the orefield is predicted. Then, the prospecting direction is pointed out.