Abstract: With analysis and sum-up of the regional geology, geochemistry and mineral resources of the Wengquangou ironboron deposit in Liaoning province, the geological-geochemical prospecting model for the marine volcanic-sedimentary metamorphic type of deposit is preliminarily established as follows:The Lieryu Formation, Liaohe Group of Paleoproterozoic Erathem is the boron-bearing formation with a stable horizon, high metamorphic degree, intensive magmatic activities and complicated structures. The anomaly assemblage of B, MgO and Fe₂O₃ appears in the orefield and areas with similar geological background. Each element has significant concentration centers in the high-value areas, but the zonation between difference elements is not so clear. The anomalies of B and Fe₂O₃ around the deposit are well coincided, which is the geochemical prospecting indicator in the area. However, the association of B and MgO is relatively unfamiliar. The establishment of the geological-geochemical prospecting model provides an important basis for the delineation of prospective areas, choice of targets and estimation of resources of the deposits of the same type.