Abstract: Combining multi-disciplinary theories and methods like environgeology and physiography for field investigation and mathematical model calculation of indoor collected data, this paper systematically studies the space-time distribution regularity of the geological disaster of landslide in Zhenxiong County. Based on the GIS overlay analysis function, the major disaster-inducing factors of landslide are obtained. By quantizing each factor with certainty factor (CF) method, a multiple linear regression model with major disaster-inducing factor data and landslide-prone levels which is fit for the landslide in Zhenxiong is established. With the model, this region is zoned by the distribution of risk of landslide.