Abstract: The Dishui copper deposit in Xinjiang Uygur Autonomous Region, a typical Cenozoic lacustrine sedimentary rock-hosted deposit, lies in the southwestern margin of Kuqa depression basin. The ore bodies occur as stratiform, between the overlying grey marl and the underlying greyish white medium-grained sandstone. The copper grade is positively related to Fe²⁺ while negatively to Fe³⁺. Cuprite is the major ore mineral. The synthetic research indicates that the Dishui copper deposit experienced several genetic stages such as syn-sedimentary, diagenetic reformation and oxidation leaching. The deposit belongs to sedimentary transformation lacustrine sedimentary rock-hosted copper deposit.