Abstract: Through the correlation analysis of the representative drill holes in the talc deposits founded in Erhulai area, Eastern Liaoning, the metallogenic factors are summarized in three aspects. First, the metallogenic rocks are the dolomite marble and silicon-bearing dolomitic marble of Paleoproterozoic Dashiqiaoan formation. Second, the ore-forming fluid is the silicate hydrothermal solution intruded in Yanshanian. And third, the leading factors that control the shapes, occurrences and spatial distributions of the orebodies are the fault belts and interbedded fractures, which are affected by the regional E-W-trending structure. Based on the study of metallogenic characteristics, the prospecting targets are predicted.