Abstract: Donggouying basin is located in the north section of Zhalantun uranium metallogenic prospective belt, with superior mineralizing geological conditions. Due to the thick forest coverage and poor transportation, the degree of uranium geological survey is low and prospecting progress is slow. Based on the regional uranium mineralization geological background, by analyzing the ore-controlling factors of typical uranium occurrences, combined with the multi-source information of airborne radioactivity, geochemistry and remote sensing, the paper constructs the integrated prospecting model for volcanic-type uranium deposits. Compared with the typical volcanic-type uranium deposits in adjacent areas, the prospect analysis concludes that the study area has a good prospecting potential. According to the prospecting model, combined with the geological, physical-chemical-remote sensing integrated prospecting information, 4 favorable areas for uranium mineralization are delineated, among which 3 are newly-delineated, with superior metallogenic conditions, abundant prospecting clues and good prospecting potential.