Abstract: On the basis of 1:50000 mineral prospective survey in Dubaoshan area and gold deposit general prospecting results in Bogenli area of Nenjiang City, Heilongjiang Province, the paper comprehensively analyzes the regional metallogenic regularity, characteristics of geophysical-geochemical anomalies and prospecting potential. The 1:50000 geochemical anomaly characteristics show that Au anomaly is dominant, with high anomaly strength, most reaching the inner zone and closely related to Ag anomaly. Six comprehensive anomalies are delineated combined with the 1:50000 geophysical prospecting characteristics and remote sensing information. For the 08XHt-3 anomaly, the Au-20 anomaly area is 3.79 km² with the maximum value of 43.1×10^-9, averagely 7.53×10^-9, reaching the inner zone. In the 08DHt-11, the Au-47 anomaly area is 2.157 km² with the maximum value of 29.9×10^-9, averagely 8.58×10^-9, reaching the inner zone. The later geophysical-geochemical prospecting in 1:10000 scale shows good reproducibility of Au anomaly, which is consistent with geophysical anomaly. The maximum Au anomaly value of delineated BG12HtAu-22 is 115.9×10^-9, averagely 23.55×10^-9, reaching the inner zone. The maximum Au anomaly values of BG12HtAu-42 and BG12HtAu-43 are 43.6×10^-9 and 25.7×10^-9 respectively, both reaching the middle zone. Through comprehensive analysis of the regional metallogenic regularity and mineralization conditions in the study area, combined with the characteristics of geophysical-geochemical anomalies and 1 gold orebody and 5 mineralized bodies discovered by a few engineering verification, it is considered that the study area has great prospecting potential and is worthy of further investigation.