Abstract: Through the study of uranium source condition, tectonic setting, geological characteristics of ore-bearing formation and oxidation-reduction condition in Taikang area, the paper analyzes the metallogenic conditions of sandstone uranium deposit in Sifangtai Formation. It is considered that the uranium-rich rocks in the west and north of Songliao Basin provide abundant uranium source. The Sifangtai Formation necessarily has a mud-sand-mud structure, a good recharge-runoff-discharge system and oxidation-reduction condition for mineralization. The uranium industrial holes and mineralized holes are obtained in the sand body at the bottom of Sifangtai Formation, indicating a good prospect in mineralization and exploration of sandstone uranium with the prospecting type of interlayer oxidation zone.