Abstract: Through the 1:50 000 geochemical survey of stream sediments in Chahaxili area, the paper analyzes the geochemical characteristics of 16 elements such as Au and Cu. Combined with the enrichment, differentiation, and superposition degree of elements, it is found that Au, Cu, Ni, Cr and Co have the possibility of enrichment and mineralization, and serve as the main ore-forming elements in the study area. Based on the anomaly characteristics and metallogenic geological conditions, it is inferred that there are structural altered rock type Au-Cu polymetallic deposits and hydrothermal alteration type Cu-Ni polymetallic deposits in the area. Four metallogenic prospective areas are optimized, including Kederite-Bagahaersan Au-Cu polymetallic prospective area, Chaganregegou Cu polymetallic prospective area, Wulanke Ni polymetallic prospective area and Manitegounan Fe-Ni polymetallic prospective area.