Abstract: Taking Xingshan County of Hubei Province in the Three Gorges reservoir region as an example, the paper comprehensively analyzes the historical landslide data and inducing factors, and evaluates the landslide susceptibility based on the weights-of-evidence method. First, ArcGIS is used to extract the evaluation factor layers including elevation, slope gradient, aspect, curvature, fault, engineering geological rock group, water system and vegetation index, and divide the evidence layer according to the frequency ratio of each evaluation factor. Secondly, the weights-of-evidence method is adopted to calculate the weight and posterior probability of each evidence layer. Then the posterior probability of each evidence layer is superimposed to generate the landslide susceptibility zoning map. Finally, the study area is divided with the quantile regression method into extremely high, high, medium and low risk areas in terms of landslide susceptibility degree. The evaluation accuracy of 86.1% for the method verified by receiver operating characteristic curve indicates that the evaluation effect is good, which can provide technical basis for risk control of local geological disasters.