Abstract: In soil-crop system, the absorption of elements such as Cd and As by crops is related to complicated factors, among which the interaction between elements is one of the majors affecting the bio-enrichment coefficient. To study the interaction between heavy metal elements in soil-rice system, 89 groups of rice seed and root soil samples are collected in Qing'an area, a typical rice production base in Heilongjiang Province, and heavy metal contents in the samples are tested. The correlation analysis is used to study the relationship between heavy metals in rice seed and root soil. The results show a positive correlation between heavy metal enrichment coefficients of rice seed. The enrichment coefficient of Cd in seed is negatively correlated with Se in soil, as well as the enrichment coefficient of Cu in seed with TOC in soil. Heavy metals in seed mostly have a positive correlation. There is a positive correlation between Zn in seed and As in soil, and a negative correlation between Cu in seed and Cd in soil. In the soil-rice system of the study area, the factors affecting the absorption of heavy metals by rice seed are very complex, with various synergistic and antagonistic interactions between elements, and their interactions need to be further studied.