Abstract: The new round of prospecting breakthrough strategic action in Northeast China, aiming at the construction of large resource bases, focusing on strategic minerals in short supply, based on the four-level zones, i.e. fundamental survey zone, key survey zone, important exploration area and significant mine, has initially formed a new prospecting layout of national-local-enterprise pattern, which has supported the establishment of a new coordination mechanism guided by the government, with association of public welfare, industry and sci-tech breakthrough, and established a three-level(national, regional and provincial) technical support business system. Based on the characterization of Daxinganling metallogenic belt, eastern Liaoning-southern Jilin metallogenic belt, eastern Jilin-Heilongjiang metallogenic belt, eastern section of northern margin of North China craton, Songliao Basin and its peripheral metallogenic areas, the paper systematically analyzes the main minerals and prospecting potential of 12+1 large resource bases, defines the work deployment of the four-level zones, and points out key problems to be solved urgently in ore prospecting in Northeast China, so as to better support the national energy resources security and overall revitalization of Northeast China in the new era.