Abstract: The Qiangkounan silver polymetallic orefiled is located in the eastern section of East Kunlun polymetallic metallogenic belt. Four integrated anomalies (AS1-AS4) dominated by Ag, Cu, Pb, Zn and Mo are identified by the 1:25000 scale trench sediment survey. Through anomaly verification, 9 mineralized zones and 21 ore (mineralized) bodies are delineated with good prospecting results. The Ag, Ag-Pb-Zn and Ag-Au-As high value areas in Ⅶ, Ⅷ and Ⅸ ore belts of AS1 and AS2 anomalies are determined by further anomaly verification, which shows a good prospect for Ag-polymetallic deposit in the area. Many Cu-polymetallic ore (mineralized) bodies are found in the deep ore-bearing granite porphyry bodies in AS3 anomaly with strong wall rock alteration, indicating good porphyry Cu-polymetallic deposit prospecting potential, while theⅠ-Ⅲ gold mineralized belts in AS4 anomaly have good prospects for Au-polymetallic deposit. From the above, the favorable metallogenic conditions, developed geochemical anomalies and informative clues of Ag-polymetallic ore prospecting fully show that the area has great prospecting potential.