Abstract: The Weihe Basin, located on Ordos block to the north and Qinling orogenic belt to the south, is a typical graben basin with complex tectonic activities, thickly-bedded Cenozoic strata and rich resources. Based on the drilling-logging data, field investigation, experiment analysis and previous research results, the Cenozoic strata in the basin is redivided and the water-gas resource types and reservoir characteristics are analyzed in depth. The results show that the basin is rich in water-gas resources, including mainly geothermal (water), mineral water, ground water, water soluble gas, biogas, helium, radon and hydrogen. The aquifers are of mainly Paleogene and Neogene bedrock fissure-pore and Quaternary gravel pore types with good water-bearing property. The Honghe, Bailuyuan, Koujiacun-Lengshuigou and Lantian-Bahe formations serve as the major geothermal reservoirs, mostly with mesopore and medium permeability, showing generally good properties. As for the gas reservoir, in addition to the thermal reservoirs, there is the Zhangjiapo Formation with good physical property, belonging to high quality reservoir. Finally, the problems existed during the water-gas resources research in the study area are analyzed as well.