Abstract: The Northern Daxinganling area, covered by primeval forest, marsh and frozen earth, is one of the most important regions for Au-Cu polymetallic metallogensis. The chief problems effecting the regional exploration are in basic geology, regional eroding depth, the explanation and using of regional geochemistry, the study and selection of exploration methods, etc. The urgency and necessity, as well as the possibility and way to solve the problems, are discussed on the basis of a detailed analysis.