Abstract: In this paper, the authors has introduced the geological background of mineralization and geology and geochemical features of Qiyugou gold deposit, discussed the genesis of ore de-posit.Through the research on the feature of rock body mineralogy, S, Pb, H and O isotopic geology and fluid inclusion of the ore-bearing breccia body, the authors conside that the ore-forming material mainly came from the underlying Taihua Group of Archean eonothem. Gas-liquid explosive breccia body is the host structure.Mineralization went on under the condition of gas-liquid explosion-boiling action after Mesozoic magmatic activity stage. Mineralizing fluid is mainly magmatic water, and mixed with part of meteorological water.The genesis of ore deposit belong to magmatic hydrothermal deposit.